Biomaterial Database

Analysis of polychlorinated dibenzo-p-dioxins and dibenzofurans in chlorinated phenols by mass fragmentography. 1975

H R Buser

A rapid, highly specific method for the analysis of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in pentachlorophenol and other chlorinated phenols is described. The rapid sample preparation procedure includes an alkaline extraction of phenolic compounds and chromatography of the neutral substances on an alumina micro-column. After gas chromatographic separation, individual polychlorinated dibenzo-p-dioxins and dibenzofurans are detected and quantified by mass fragmentography. The sample purification procedure removes polychlorinated diphenyl ethers, polychlorinated biphenyls and benzenes, phthalates and polychlorinated phenoxyphenols (predioxins), which might otherwise severely interfere in the analysis. Significant levels of hexa-, hepta- and octachlorodibenzo-p-dioxin and of hexa-, hepta- and octachlorodibenzofuran were found in two commercial products.

UI	MeSH Term	Description	Entries
D010647	Phenyl Ethers	Ethers that are linked to a benzene ring structure.	Diphenyl Oxide,Diphenyl Oxides,Diphenyl Ethers,Ethers, Diphenyl,Ethers, Phenyl,Oxide, Diphenyl,Oxides, Diphenyl
D011078	Polychlorinated Biphenyls	Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.	PCBs,Polychlorinated Biphenyl,Polychlorobiphenyl Compounds,Biphenyl, Polychlorinated,Biphenyls, Polychlorinated,Compounds, Polychlorobiphenyl
D002845	Chromatography	Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts.	Chromatographies
D002849	Chromatography, Gas	Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.	Chromatography, Gas-Liquid,Gas Chromatography,Chromatographies, Gas,Chromatographies, Gas-Liquid,Chromatography, Gas Liquid,Gas Chromatographies,Gas-Liquid Chromatographies,Gas-Liquid Chromatography
D004147	Dioxins	A family of compounds that contain the 1,4-dioxin structure. Many specific dioxin derivatives are listed as CARCINOGENS; TERATOGENS; or MUTAGENS.	Dioxin
D000535	Aluminum	A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.	Aluminium,Aluminium-27,Aluminum-27,Aluminium 27,Aluminum 27
D001572	Benzofurans	Compounds that contain a BENZENE ring fused to a furan ring.	Coumarones,Diphenylbenzofuran
D013058	Mass Spectrometry	An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.	Mass Spectroscopy,Spectrometry, Mass,Spectroscopy, Mass,Spectrum Analysis, Mass,Analysis, Mass Spectrum,Mass Spectrum Analysis,Analyses, Mass Spectrum,Mass Spectrum Analyses,Spectrum Analyses, Mass