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Measurements of blood and liver water-soluble vitamins and of their metabolites urinary excretion helped characterize these vitamins metabolism in rats with streptozotocin-induced diabetes. The liver levels of recovered ascorbic acid and total thiamin were virtually the same in diabetic and intact rats. Essential changes of riboflavin metabolism were revealed in diabetes: riboflavin urinary excretion was five times higher than that in intact animals, the blood serum levels being the same in health and disease, whereas liver riboflavin levels in diabetic rats had a trend to lowering. The activities of FAD-dependent hepatic enzymes were the same in both groups. 4-pyridoxylic acid excretion was increased and 1-methylnicotinamide excretion reduced in diabetic rats.
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
September 1984,
Current eye research,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
January 1988,
Archives internationales de pharmacodynamie et de therapie,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
June 1969,
Lancet (London, England),
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
January 2012,
Journal of nutritional science and vitaminology,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
January 1990,
Fundamental & clinical pharmacology,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
January 1980,
Acta neuropathologica,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
August 1996,
Journal of endodontics,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
October 2017,
Journal of cellular physiology,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
June 1979,
The Biochemical journal,
R E Sadykova, and
V M Kodentsova, and
A A Sokol'nikov, and
O A Vrzhesinskaia, and
N A Beketova, and
A V Dreval', and
V Iu Spirichev
February 1999,
Clinical science (London, England : 1979),
