-transparent.png){kind=logo}
The transcatheter injection of fibrinolytic agents is now the treatment of choice of the acute occlusions of the peripheral arteries. We retrospectively compared the efficacy and safety of two fibrinolytic agents (urokinase and recombinant tissue-type plasminogen activator) in 83 consecutive patients: 37 with occlusion of surgical bypass grafts, 36 with occlusion of atheromatous vessels, 5 with post-angioplasty occlusion, 2 with post-traumatic thrombosis, 2 with cardiogenic emboli and 1 with thrombophilia. Recanalization was achieved in 55 of 59 (93%) patients treated with urokinase and in 21 of 24 (88%) patients treated with recombinant tissue-type plasminogen activator (p > 0.05). The latter provided a more rapid recanalization than urokinase but was also responsible for the complications observed in all 10 (12%) patients. These results indicate that urokinase is to be preferred to recombinant tissue type plasminogen activator for routine arterial transcatheter fibrinolysis.
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
January 1991,
Radiology,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
December 1995,
Protein engineering,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
October 1991,
Thrombosis and haemostasis,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
December 2012,
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
July 1999,
Journal of cataract and refractive surgery,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
January 2007,
The international journal of biochemistry & cell biology,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
January 1996,
Polish journal of pharmacology,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
January 1992,
Thrombosis and haemostasis,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
January 1997,
Journal of vascular surgery,
C Vignali, and
R Cioni, and
M Mascalchi, and
R Russo, and
A Palla, and
R Lencioni, and
V Napoli, and
C Bartolozzi
March 1991,
The Journal of biological chemistry,
