Pulmonary arterial hypertension in patients with secundum atrial septal defects. 1994

A Bharani, and S Shrivastava, and R Tandon
All India Institute of Medical Sciences, Ansari Nagar, New Delhi.

BACKGROUND Experience in Vellore suggests that pulmonary arterial hypertension develops at an earlier age in Indian patients with secundum atrial defects than it does in westerners. We examined the haemodynamic data on patients with secundum atrial defects to determine whether this was also true in Delhi. METHODS We analysed the data on 461 patients with secundum atrial defects, grouping them according to their pulmonary (Qp) and systemic (Qs) flow rates as well as the ratio of pulmonary to systemic systolic pressure (Pap/Sap) into 4 groups: [table: see text] RESULTS There were 8 (2%) patients in group 1, 282 (61%) in group 2, 124 (27%) in group 3, 28 (6%) in group 4a and 19 (4%) in group 4b. Of the 19 patients in group 4b, 6 (1%) were below 20 years of age and 13 (3%) above 20 years. CONCLUSIONS Our findings indicate that obstructive pulmonary arterial hypertension does not develop early in patients in Delhi.

UI MeSH Term Description Entries
D006976 Hypertension, Pulmonary Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES. Pulmonary Hypertension
D007194 India A country in southern Asia, bordering the Arabian Sea and the Bay of Bengal, between Burma and Pakistan. The capitol is New Delhi. Republic of India
D007223 Infant A child between 1 and 23 months of age. Infants
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D006344 Heart Septal Defects, Atrial Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects. Atrial Septal Defects,Ostium Primum Atrial Septal Defect,Persistent Ostium Primum,Atrial Septal Defect,Atrial Septal Defect Ostium Primum,Ostium Secundum Atrial Septal Defect,Defect, Atrial Septal,Ostium Primum, Persistent,Primum, Persistent Ostium,Septal Defect, Atrial
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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