Cortical bone density of the proximal femur following cementless total hip arthroplasty. 1994

T F McGovern, and C A Engh, and K Zettl-Schaffer, and J P Hooten
Anderson Orthopaedic Research Institute, Arlington, VA 22206.

A quantitative analysis of cortical bone remodeling was performed using calibrated videodensitometry. Six femoral specimens were obtained at autopsy from 3 patients treated with unilateral porous coated femoral components in situ > 6 years. Transverse thick sections of the remodeled and normal femora were obtained. Slab radiographs of the sections were analyzed using computer assisted videodensitometry. Detailed density plots of each section were constructed and the average density in defined quadrants was recorded. The density plots were also used to measure the cortical bone area present on each section. Two cases showed a gradient of resorptive remodeling change with the greatest density loss noted medially at the proximal levels (33% and 36%). The 3rd case had porotic cortical bone in the normal femur and demonstrated a different remodeling pattern, with the greatest average resorptive change (57%) measured in the midstem region. Changes in cortical area were variable: 1 showed cortical thickening in the midstem region; another had decreased cortical area in the entire region adjacent to the porous coating; and the 3rd had decreased cortical area proximally, with minimal changes noted in the distal levels. The volumetric densities measured by videodensitometry were compared with area densities measured with dual energy xray absorptiometry. There was a strong linear correlation between the 2 methods (r2 = 0.80).

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D001862 Bone Resorption Bone loss due to osteoclastic activity. Bone Loss, Osteoclastic,Osteoclastic Bone Loss,Bone Losses, Osteoclastic,Bone Resorptions,Loss, Osteoclastic Bone,Losses, Osteoclastic Bone,Osteoclastic Bone Losses,Resorption, Bone,Resorptions, Bone
D005260 Female Females
D005269 Femur The longest and largest bone of the skeleton, it is situated between the hip and the knee. Trochanter,Greater Trochanter,Lesser Trochanter,Femurs,Greater Trochanters,Lesser Trochanters,Trochanter, Greater,Trochanter, Lesser,Trochanters,Trochanters, Greater,Trochanters, Lesser
D006622 Hip Prosthesis Replacement for a hip joint. Femoral Head Prosthesis,Femoral Head Prostheses,Hip Prostheses,Prostheses, Femoral Head,Prostheses, Hip,Prosthesis, Femoral Head,Prosthesis, Hip
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old

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