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The value of automated DNA cytometry for differentiation of testis cancer was evaluated in 54 seminomas, 13 HCG-positive seminomas, and 48 embryonal carcinomas. Slices of paraffin embedded tissue were enzymatically digested and stained with Feulgen SITS after fixation on glass slides. Automated DNA cytometry was performed with a Modular Image Analysis Computer (MIAC). DNA histogram phenotpye and computed DNA indices were correlated with the different tumor types. The ratio of hypertriploid to hypotriploid increased from HCG-positive seminoma over embryonal carcinoma to seminoma. The following mathematical DNA indices were found to correlate with tumor type: mean ploidy, 2c deviation index, 5c exceeding rate, variation coefficient of the GO/1 fraction and DNA nucleus diameter correlation.
R A Bürger, and
U Witzsch, and
H Engel, and
D Potratz, and
M Stöckle
January 1993,
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer,
R A Bürger, and
U Witzsch, and
H Engel, and
D Potratz, and
M Stöckle
January 1997,
European urology,
R A Bürger, and
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H Engel, and
D Potratz, and
M Stöckle
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Oral diseases,
R A Bürger, and
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M Stöckle
November 1991,
Cancer,
R A Bürger, and
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D Potratz, and
M Stöckle
January 2013,
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference,
R A Bürger, and
U Witzsch, and
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M Stöckle
August 1985,
Cancer letters,
R A Bürger, and
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M Stöckle
January 1990,
Verhandlungen der Deutschen Gesellschaft fur Pathologie,
R A Bürger, and
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M Stöckle
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Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen,
R A Bürger, and
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H Engel, and
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M Stöckle
November 1994,
Japanese journal of cancer research : Gann,
R A Bürger, and
U Witzsch, and
H Engel, and
D Potratz, and
M Stöckle
August 1994,
Pathologica,
