[Effects of selective proximal vagotomy on gastrin, glucagon and insulin contents in blood of patients with duodenal ulcer]. 1994

M G Shevchuk, and A L Shapoval, and E A Ostapenko, and R P Gerich, and V P Protsiuk

Content of gastrin, glucagon and insulin in the blood of 49 patients with a duodenal ulcer was similar to that in control group patients. Significant increase in gastrin and glucagon levels, decrease in insulin content was noted 14-15 days after the performance of selective proximal vagotomy. At the late period, concentration of the hormones studied was within the limits of physiologic levels. The data obtained permit to assess the completeness of vagotomy and to predict the long-term result of the operation.

UI MeSH Term Description Entries
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D004381 Duodenal Ulcer A PEPTIC ULCER located in the DUODENUM. Curling's Ulcer,Curling Ulcer,Curlings Ulcer,Duodenal Ulcers,Ulcer, Curling,Ulcer, Duodenal,Ulcers, Duodenal
D005755 Gastrins A family of gastrointestinal peptide hormones that excite the secretion of GASTRIC JUICE. They may also occur in the central nervous system where they are presumed to be neurotransmitters. Gastrin
D005934 Glucagon A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511) Glucagon (1-29),Glukagon,HG-Factor,Hyperglycemic-Glycogenolytic Factor,Proglucagon (33-61),HG Factor,Hyperglycemic Glycogenolytic Factor
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014629 Vagotomy, Proximal Gastric Vagal denervation of that part of the STOMACH lined with acid-secreting mucosa (GASTRIC MUCOSA) containing the GASTRIC PARIETAL CELLS. Since the procedure leaves the vagal branches to the antrum and PYLORUS intact, it circumvents gastric drainage required with truncal vagotomy techniques. Vagotomy, Highly Selective,Vagotomy, Parietal Cell,Vagotomy, Selective Proximal,Gastric Vagotomies, Proximal,Gastric Vagotomy, Proximal,Highly Selective Vagotomies,Highly Selective Vagotomy,Parietal Cell Vagotomies,Parietal Cell Vagotomy,Proximal Gastric Vagotomies,Proximal Gastric Vagotomy,Proximal Vagotomies, Selective,Proximal Vagotomy, Selective,Selective Proximal Vagotomies,Selective Proximal Vagotomy,Selective Vagotomies, Highly,Vagotomies, Highly Selective,Vagotomies, Parietal Cell,Vagotomies, Proximal Gastric,Vagotomies, Selective Proximal

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