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The objective of our work was to carry out a prospective study on the effectiveness of clonidine and nicotine gum in the treatment of tobacco withdrawal. Sixty smokers were randomly distributed in two groups and were included in a tobacco withdrawal program. One group received oral clonidine treatment while the other group was given nicotine gum. Adjuvant therapy such as group therapy or psychotherapy was not performed. At the end of one year there were no significant differences between the two groups with regards to the number of subjects who have continued to stop smoking. There were also no significant differences between the two groups with regards to the symptoms of tobacco abstinence. When we studied the relation between treatment fulfillment and tobacco withdrawal we observed that the clonidine treated group had a significantly greater number of success compared to the nicotine group (p < 0.01).
M Aparici, and
A L Fernández González, and
E Alegría
January 1997,
Addictive behaviors,
M Aparici, and
A L Fernández González, and
E Alegría
July 1984,
Ugeskrift for laeger,
M Aparici, and
A L Fernández González, and
E Alegría
January 1982,
The Practitioner,
M Aparici, and
A L Fernández González, and
E Alegría
June 1985,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
M Aparici, and
A L Fernández González, and
E Alegría
September 1976,
British medical journal,
M Aparici, and
A L Fernández González, and
E Alegría
August 1987,
Lancet (London, England),
M Aparici, and
A L Fernández González, and
E Alegría
September 1982,
British medical journal (Clinical research ed.),
M Aparici, and
A L Fernández González, and
E Alegría
October 1984,
Annals of internal medicine,
M Aparici, and
A L Fernández González, and
E Alegría
June 1984,
Connecticut medicine,
M Aparici, and
A L Fernández González, and
E Alegría
February 1985,
Lancet (London, England),
