-transparent.png){kind=logo}
The structure of the glycan moiety of the glycosylphosphatidylinositol (GPI) membrane anchor from Torpedo californica electric organ acetylcholinesterase was solved using nuclear magnetic resonance (NMR), methylation analysis, and chemical and enzymic microsequencing. Two structures were found to be present: Glc alpha 1-2 Man alpha 1-2 Man alpha 1-6 Man alpha 1-4 GlcN alpha 1-6myo-inositol, and Glc alpha 1-2 Man alpha 1-2 Man alpha 1-6 (GalNAc beta 1-4) Man alpha 1-4 GlcN alpha 1-6myo-inositol. The presence of glucose in this GPI anchor structure is a novel feature. The anchor was also shown to contain 2.3 residues of ethanolamine per molecule.
Related Publications
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
February 1993,
Biochemical Society transactions,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
December 1985,
European journal of biochemistry,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
January 1975,
Zhurnal evoliutsionnoi biokhimii i fiziologii,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
September 1983,
Neuroscience letters,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
October 1979,
The Journal of biological chemistry,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
December 1976,
Molecular and cellular biochemistry,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
February 2007,
Proteomics,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
August 1992,
Biochemistry international,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
October 1980,
FEBS letters,
A Mehlert, and
L Varon, and
I Silman, and
S W Homans, and
M A Ferguson
October 1992,
Journal of neurocytology,
