Prestimulus EEG-activity strongly influences the auditory evoked vertex response: a new method for selective averaging. 1993

E Rahn, and E Başar
Institute of Physiology, Medical University, Lübeck, Germany.

A new algorithm for averaging of evoked potentials (EPs) is introduced and compared with the conventional method. The root mean square (rms) values of the alpha and theta band EEG activities 1-s preceding stimulus presentation were computed: stimuli were blocked during phases of high prestimulus activity, thus evoking auditory responses selectively during periods of low activity. Ten volunteers were stimulated with tone bursts of 2000 Hz, 80 dB and 1-s duration. The main results were: (1) The averaged EPs showed an increase in amplitude of nearly 40% in comparison to experiments with conventional stimulation. This increase was in the range of 30% when an ISI correction was taken into account. (2) Single trials tended to form patterns of damped oscillations of e.g., 7-8 Hz, thus revealing a high correlation to the averaged EP. In alpha or theta band contingent experiments, correlation coefficients between single trials and averaged EPs were significantly higher (p < .01; p < .05).

UI MeSH Term Description Entries
D008297 Male Males
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D003071 Cognition Intellectual or mental process whereby an organism obtains knowledge. Cognitive Function,Cognitions,Cognitive Functions,Function, Cognitive,Functions, Cognitive
D004569 Electroencephalography Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain. EEG,Electroencephalogram,Electroencephalograms
D005072 Evoked Potentials, Auditory The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS. Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000513 Alpha Rhythm Brain waves characterized by a relatively high voltage or amplitude and a frequency of 8-13 Hz. They constitute the majority of waves recorded by EEG registering the activity of the parietal and occipital lobes when the individual is awake, but relaxed with the eyes closed. Alpha Rhythms,Rhythm, Alpha,Rhythms, Alpha
D013826 Theta Rhythm Brain waves characterized by a frequency of 4-7 Hz, usually observed in the temporal lobes when the individual is awake, but relaxed and sleepy. Rhythm, Theta,Rhythms, Theta,Theta Rhythms

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