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Fifty-seven inpatients with major depression (DSM-III-R) entered a 12-week study comparing paroxetine and imipramine. Trends (not reaching statistical significance) in favour of paroxetine were seen on the Hamilton Depression Rating Scale (HDRS) and the Montgomery-Asberg Depression Rating Scale (MADRS). The UKU Side Effect Rating Scale showed a significant difference in favour of paroxetine on reduced salivation. Global evaluation of side effect symptoms showed that significantly more paroxetine patients had no side effects, both in the investigators' and the patients' opinion. These results are in line with previous findings of paroxetine being an effective and well tolerated antidepressant.
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
January 1993,
International clinical psychopharmacology,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
February 1992,
The Journal of clinical psychiatry,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
June 1992,
International clinical psychopharmacology,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
December 1973,
Current therapeutic research, clinical and experimental,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
June 1993,
Journal of affective disorders,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
April 1989,
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
December 1992,
The Journal of clinical psychiatry,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
January 1989,
Acta psychiatrica Scandinavica. Supplementum,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
May 1997,
Pharmacopsychiatry,
S L Arminen, and
U Ikonen, and
P Pulkkinen, and
E Leinonen, and
A Mahlanen, and
H Koponen, and
K Kourula, and
J Ryyppö, and
V Korpela, and
M L Lehtonen
June 1992,
International clinical psychopharmacology,
