Scotopic threshold response in complete and incomplete types of congenital stationary night blindness. 1994

Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
Department of Ophthalmology, Nagoya University School of Medicine, Japan.

OBJECTIVE To study the function of the rod visual pathway in the complete and incomplete types of congenital stationary night blindness (CSNB), with special reference to the scotopic threshold response (STR) of electroretinograms (ERGs) METHODS Using full-field stimuli with light intensities ranging from near absolute threshold to bright, ERG intensity series from two patients with complete CSNB, four patients with incomplete CSNB, and four normal subjects were recorded. RESULTS Neither the rod b-wave nor the STR was recordable from the patients with complete CSNB. In the patients with incomplete CSNB, the STR was clearly recorded, although the absolute threshold was elevated in accordance with elevation of the psychophysical absolute threshold. The b-wave stimulus threshold was not elevated, and the b-wave amplitude near the threshold was normal. The peak time of the STR was delayed by approximately 80 msec, whereas that of the b-wave was normal. CONCLUSIONS These STR results indicate that the rod system abnormality in complete CSNB differs from that in incomplete CSNB. Furthermore, the greatly delayed peak time of STR in the patients with incomplete CSNB made the interaction between b-wave and STR different from that in normal subjects.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009755 Night Blindness Failure or imperfection of vision at night or in dim light, with good vision only on bright days. (Dorland, 27th ed) Nyctalopia,Blindness, Night
D010775 Photic Stimulation Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity. Stimulation, Photic,Visual Stimulation,Photic Stimulations,Stimulation, Visual,Stimulations, Photic,Stimulations, Visual,Visual Stimulations
D011601 Psychophysics The science dealing with the correlation of the physical characteristics of a stimulus, e.g., frequency or intensity, with the response to the stimulus, in order to assess the psychologic factors involved in the relationship. Psychophysic
D004596 Electroretinography Recording of electric potentials in the retina after stimulation by light. Electroretinographies
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
September 2003, Documenta ophthalmologica. Advances in ophthalmology,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
July 2004, Documenta ophthalmologica. Advances in ophthalmology,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
January 2018, Advances in experimental medicine and biology,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
April 1986, Acta ophthalmologica,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
July 1996, Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
January 2004, Klinika oczna,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
May 2006, [Zhonghua yan ke za zhi] Chinese journal of ophthalmology,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
September 2002, American journal of ophthalmology,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
December 2002, Nippon Ganka Gakkai zasshi,
Y Miyake, and M Horiguchi, and H Terasaki, and M Kondo
January 1996, Klinische Monatsblatter fur Augenheilkunde,
Copied contents to your clipboard!