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Three millilitres of plain 0.5% bupivacaine were injected intrathecally at two different spinal interspaces (L2/3 and L4/5) and at two different speeds (15 and 30 sec) in four groups of ten patients. Injection at L2/3 over 15 sec produced a significantly higher mean maximum spread of analgesia (T6.4) when compared to injection at L4-5 over 15 sec (T10.3) (P < 0.05). Over the same interspace L2/3, injection over 15 sec also produced a higher level of spread as compared to the 30 sec group (p < 0.05). At 15 min there was a greater fall in blood pressure in the L2/3 15 sec group when compared to the other groups (p < 0.01). There was a further decrease in the blood pressure in L2/3 15 sec and L4/5 30 sec groups after 30 minutes of blockade (p < 0.01). Therefore close monitoring of cardiovascular parameters must be continued for at least 30 min in spinal anaesthesia with bupivacaine.
K W Chin, and
N M Chin, and
M K Chin
April 1989,
British journal of anaesthesia,
K W Chin, and
N M Chin, and
M K Chin
August 1992,
British journal of anaesthesia,
K W Chin, and
N M Chin, and
M K Chin
April 1991,
British journal of anaesthesia,
K W Chin, and
N M Chin, and
M K Chin
November 1989,
Acta anaesthesiologica Scandinavica,
K W Chin, and
N M Chin, and
M K Chin
December 2000,
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K W Chin, and
N M Chin, and
M K Chin
September 1984,
Anaesthesia,
K W Chin, and
N M Chin, and
M K Chin
May 1990,
British journal of anaesthesia,
K W Chin, and
N M Chin, and
M K Chin
March 1984,
British journal of anaesthesia,
K W Chin, and
N M Chin, and
M K Chin
December 2002,
Der Anaesthesist,
K W Chin, and
N M Chin, and
M K Chin
September 1996,
British journal of anaesthesia,
