Biomaterial Database

Effect of hyperbaric helium on vitamin uptake and utilization by micro-organisms. 1975

V Frattali, and R Robertson

Growth responses under hyperbaric helium of various procaryotic micro-organisms to graded levels of six water-soluble vitamins were measured. Vitamins included: thiamin, riboflavin, niacin, pantothenic acid, biotin, and folic acid (folacin). Growth response of each organism under hyperbaric helium was compared with that under 80% He-20% O2 and other He-O2 gas mixtures at atmospheric pressure, and with response in air at atmospheric pressure. For five of the six vitamins, no differences in response were observed. Growth response of Streptococcus faecalis to growth-limiting concentrations of folic acid was depressed during cultivation under He-O2 at 69 ATA. It is concluded that growth response of the organism is repressed by hyperbaric helium as a result of interference with uptake or utilization of the vitamin.

UI	MeSH Term	Description	Entries
D007777	Lactobacillaceae	A family of gram-positive bacteria found regularly in the mouth and intestinal tract of man and other animals, in food and dairy products, and in fermenting vegetable juices. A few species are highly pathogenic.
D007778	Lactobacillus	A genus of gram-positive, microaerophilic, rod-shaped bacteria occurring widely in nature. Its species are also part of the many normal flora of the mouth, intestinal tract, and vagina of many mammals, including humans. Lactobacillus species are homofermentative and ferment a broad spectrum of carbohydrates often host-adapted but do not ferment PENTOSES. Most members were previously assigned to the Lactobacillus delbrueckii group. Pathogenicity from this genus is rare.
D004780	Environment, Controlled	A state in which the environs of hospitals, laboratories, domestic and animal housing, work places, spacecraft, and other surroundings are under technological control with regard to air conditioning, heating, lighting, humidity, ventilation, and other ambient features. The concept includes control of atmospheric composition. (From Jane's Aerospace Dictionary, 3d ed)	Clean Rooms,Laminar Air-Flow Areas,Controlled Environment,Area, Laminar Air-Flow,Clean Room,Controlled Environments,Environments, Controlled,Laminar Air Flow Areas,Laminar Air-Flow Area,Room, Clean
D006371	Helium	A noble gas with the atomic symbol He, atomic number 2, and atomic weight 4.003. It is a colorless, odorless, tasteless gas that is not combustible and does not support combustion. It was first detected in the sun and is now obtained from natural gas. Medically it is used as a diluent for other gases, being especially useful with oxygen in the treatment of certain cases of respiratory obstruction, and as a vehicle for general anesthetics.	Helium-4,Helium 4
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001274	Atmospheric Pressure	The pressure at any point in an atmosphere due solely to the weight of the atmospheric gases above the point concerned.	Atmospheric Pressures,Pressure, Atmospheric,Pressures, Atmospheric
D013293	Enterococcus faecalis	A species of gram-positive, coccoid bacteria commonly isolated from clinical specimens and the human intestinal tract. Most strains are nonhemolytic.	Streptococcus Group D,Streptococcus faecalis
D014803	Vitamin B Complex	A group of water-soluble vitamins, some of which are COENZYMES.	B Vitamin,B Vitamins,Neurobion,Vitamin, B
D014815	Vitamins	Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.	Vitamin