Biomaterial Database

Transcutaneous Po2 and Pco2 measurement in dermatology. 1994

H Takiwaki

Department of Dermatology, School of Medicine, University of Tokushima, Japan.

Although transcutaneous Po2 (tcPo2) and Pco2 (tcPco2) measurement was originally developed for the non-invasive Pao2 and Paco2 monitoring, its utilization in dermatology is discussed in this article. Our experimental and clinical studies have revealed that tcPo2 is easily influenced and reduced by various skin changes, such as hyperkeratosis, acanthosis, cellular infiltrate and fibrosis as well as the circulatory disturbance in the skin, and that tcPco2 is kept stable except in ischemic or bullous lesions. Although tcPo2 could be a marker reflecting the severity of some lesions, simultaneous measurement of tcPco2 and cutaneous blood flow would offer more precise information about the circulation and respiration in the skin.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010101	Oxygen Consumption	The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)	Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D002245	Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.	Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D003880	Dermatology	A medical specialty concerned with the skin, its structure, functions, diseases, and treatment.
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012867	Skin	The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012871	Skin Diseases	Diseases involving the DERMIS or EPIDERMIS.	Dermatoses,Skin and Subcutaneous Tissue Disorders,Dermatosis,Skin Disease
D017078	Laser-Doppler Flowmetry	A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.	Doppler-Laser Flowmetry,Flowmetry, Laser-Doppler,Laser-Doppler Velocimetry,Velocimetry, Laser-Doppler,Doppler Laser Flowmetry,Flowmetry, Doppler-Laser,Flowmetry, Laser Doppler,Laser Doppler Flowmetry,Laser Doppler Velocimetry,Velocimetry, Laser Doppler
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus