Biomaterial Database

[New phages of a polylysogenic culture of Actinomyces griseus]. 1975

Ia I Rautenshteĭn, and N Ia Solov'eva, and L N Moskalenko, and A D Filatova

The culture of Actinomyces griseus 15 was found to have a more complicated phage composition than it was supposed earlier. A new virulent mutant B has been isolated, which differs by its properties from the phage of Act. griseus 15, type I, isolated earlier. Phage lysates of the virulent mutants originating from different temperate phages of Act. griseus 15. Therefore, the culture of Act. griseus 15 is polylysogenic, defective lysogenic and contains at least three different phages.

UI	MeSH Term	Description	Entries
D008242	Lysogeny	The phenomenon by which a temperate phage incorporates itself into the DNA of a bacterial host, establishing a kind of symbiotic relation between PROPHAGE and bacterium which results in the perpetuation of the prophage in all the descendants of the bacterium. Upon induction (VIRUS ACTIVATION) by various agents, such as ultraviolet radiation, the phage is released, which then becomes virulent and lyses the bacterium.	Integration, Prophage,Prophage Integration,Integrations, Prophage,Prophage Integrations
D009154	Mutation	Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.	Mutations
D001435	Bacteriophages	Viruses whose hosts are bacterial cells.	Phages,Bacteriophage,Phage
D013305	Streptomyces griseus	An actinomycete from which the antibiotics STREPTOMYCIN, grisein, and CANDICIDIN are obtained.
D014774	Virulence	The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.	Pathogenicity