Biomaterial Database

Avian riboflavinuria. 10. Quantitative changes of riboflavin-binding protein in individual egg tissues during incubation. 1975

S L Tarhay, and E G Buss, and C O Clagett

The riboflavin binding protein (RBP) content of individual egg components were followed through the development of fertilized eggs. Total proteins of the tissues were analyzed. The disappearance of RBP from the yolk and albumen occurred at the same rate as the total proteins. There was no evidence of any increase of free riboflavin nor degraded RBP in the yolk and albumen. Hence, it appears that the riboflavin was taken in by the embryo as the riboflavin-protein complex. The individual embryos showed some RBP accumulation through the first fourteen days of development. This may be an indication that the embryo is taking in the riboflavin-protein complex faster than riboflavin is utilized during the early stages of incubation. However, the beginning of a more rapid rate of growth at 13-14 days, was associated with the start of a gradual decline in the level of RBP in the embryo. This may suggest that the need for riboflavin exceeds the rate of transfer from the yolk and albumen reservoirs. RBP-riboflavin complex appears to be degraded after transfer to the embryo.

UI	MeSH Term	Description	Entries
D007185	Incubators	Insulated enclosures in which temperature, humidity, and other environmental conditions can be regulated at levels optimal for growth, hatching, reproduction, or metabolic reactions.	Incubator
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D010047	Ovalbumin	An albumin obtained from the white of eggs. It is a member of the serpin superfamily.	Serpin B14
D011485	Protein Binding	The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.	Plasma Protein Binding Capacity,Binding, Protein
D011506	Proteins	Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.	Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D001826	Body Fluids	Liquid components of living organisms.	Body Fluid,Fluid, Body,Fluids, Body
D002642	Chick Embryo	The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.	Embryo, Chick,Chick Embryos,Embryos, Chick
D002645	Chickens	Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.	Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D004530	Egg Yolk	Cytoplasm stored in an egg that contains nutritional reserves for the developing embryo. It is rich in polysaccharides, lipids, and proteins.	Egg Yolks,Yolk, Egg,Yolks, Egg
D005260	Female		Females