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This experiment examined whether the imidazoline idazoxan (which binds to alpha-noradrenergic receptors and to imidazoline-preferring sites) interferes with hormone-dependent or hormone-independent lordosis responses. Ovariectomized (ovx) Strain 2 female guinea pigs which were sexually receptive after receiving estradiol benzoate (EB; 3 micrograms/d for 3 days) were injected with either idazoxan (10 mg/kg) or with vehicle at 24 hr after the last EB injection. Idazoxan significantly decreased EB-facilitated lordosis responses in these females. Castrated Strain 2 males, which show lordosis behavior without gonadal hormone administration, were injected with the same dosage of idazoxan (10 mg/kg) or with vehicle. Idazoxan did not inhibit lordosis behavior in these males.
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
April 1977,
Endocrinology,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
March 1977,
Contraception, fertilite, sexualite,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
March 1991,
Hormones and behavior,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
March 1976,
Journal of the National Cancer Institute,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
May 1969,
Igaku to seibutsugaku. Medicine and biology,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
January 1979,
Brain research bulletin,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
October 1971,
Physiology & behavior,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
April 1989,
Brain research,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
February 1978,
Pharmacology, biochemistry, and behavior,
J E Thornton, and
M Roy, and
P Vincent, and
R W Goy, and
B S McEwen, and
H H Feder
April 1998,
Brain research,
