Multinucleate spermatogenic cells by traumatic haemorrhagic suffusion in lizard testes. 1975

E Del Conte

During a study on testicular cycle in the tropical teiid lizard Cnemidophorus 1. lemniscatus (L.), some animals showed testicular haemorrhagic suffusions presumptively due to traumata suffered while they were captured, between 4 and 8 hours before the autopsy. Their testes were immediately removed and processed to be examined under the light microscope. The extravasated blood was always relatively scarce and limited to the interstitial spaces. Numerous multinucleate spermatogenic cells in all the stages of development were found within the seminiferous tubules contiguous to the suffered blood. The number of nuclei in these cells increases from spermatogonia, which generally have two and rarely more than four, to spermatids, which sometimes form giant cells with more than thirty nuclei. The various nuclei of each multinucleate cell pertain exactly to the same spermatogenic stage. Divisionss of the multiple nuclei proceed simultaneously but in an independent way. As relatively broad intercellular bridges between normal spermatogenic cells of each type can be seen in this species through the electron microscope, cell fusion by enlargement of the preexistent cytoplasmic interconnections is considered to be the more probable way of formation of multinucleate cells. Nuclear divisions not followed by cytokinesis may contribute in this process. A reduced exchange of materials derived from the local circulatory disturbance, and particularly hypoxia, are likely the cause of these cell alterations.

UI MeSH Term Description Entries
D008116 Lizards Reptiles within the order Squamata that generally possess limbs, moveable EYELIDS, and EXTERNAL EAR openings, although there are some species which lack one or more of these structures. Chameleons,Geckos,Chameleon,Gecko,Lizard
D008297 Male Males
D002455 Cell Division The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION. M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D002459 Cell Fusion Fusion of somatic cells in vitro or in vivo, which results in somatic cell hybridization. Cell Fusions,Fusion, Cell,Fusions, Cell
D006470 Hemorrhage Bleeding or escape of blood from a vessel. Bleeding,Hemorrhages
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000860 Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. Anoxia,Oxygen Deficiency,Anoxemia,Deficiency, Oxygen,Hypoxemia,Deficiencies, Oxygen,Oxygen Deficiencies
D013087 Spermatids Male germ cells derived from the haploid secondary SPERMATOCYTES. Without further division, spermatids undergo structural changes and give rise to SPERMATOZOA. Spermatoblasts,Spermatid,Spermatoblast
D013091 Spermatogenesis The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA. Spermatocytogenesis,Spermiogenesis
D013093 Spermatogonia Euploid male germ cells of an early stage of SPERMATOGENESIS, derived from prespermatogonia. With the onset of puberty, spermatogonia at the basement membrane of the seminiferous tubule proliferate by mitotic then meiotic divisions and give rise to the haploid SPERMATOCYTES. Spermatophores,Spermatogonias,Spermatophore

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