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Gastric bicarbonate secretion in high-relapsing, smoking duodenal ulcer patients. 1993
P Dal Santo, and
F Vianello, and
B Germana, and
T Del Bianco, and
G Laino, and
S A Grassi, and
M Plebani, and
P Dotto, and
G Battaglia, and
F Di Mario
Istituto di Medicina Interna, Università degli Studi di Padova, Italy.
Gastric bicarbonate secretion has been evaluated by Feldman's method in 48 duodenal-ulcer patients. The relationship between smoking, clinical ulcer outcome (healing and recurrence) and bicarbonate secretion has been analysed. Heavy smokers secreted higher bicarbonate ions than did non-smokers. High-relapsing patients produced lower bicarbonate output. These preliminary data suggest that an impaired gastric bicarbonate secretion is associated with smoking, a well-known ulcer-associated factor; further-more, it may single out high-relapsing duodenal ulcer patients.
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