Striatal [11C]-N-methyl-spiperone binding in patients with focal dystonia (torticollis) using positron emission tomography. 1993

K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
Paul Scherrer Institute, Villigen, Switzerland.

Specific binding of [11C]-N-methyl-spiperone to striatal dopamine D2 receptors was assessed using positron emission tomography (PET) in 6 patients with adult-onset focal dystonia (predominantly spasmodic torticollis) and in 5 healthy subjects. No significant difference in average specific striatal tracer uptake between patients and healthy subjects was found. However, in the 5 patients showing lateralisation of clinical signs a trend to higher striatal tracer uptake in the contralateral hemisphere was observed.

UI MeSH Term Description Entries
D007839 Functional Laterality Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot. Ambidexterity,Behavioral Laterality,Handedness,Laterality of Motor Control,Mirror Writing,Laterality, Behavioral,Laterality, Functional,Mirror Writings,Motor Control Laterality,Writing, Mirror,Writings, Mirror
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002540 Cerebral Cortex The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulci. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions. Allocortex,Archipallium,Cortex Cerebri,Cortical Plate,Paleocortex,Periallocortex,Allocortices,Archipalliums,Cerebral Cortices,Cortex Cerebrus,Cortex, Cerebral,Cortical Plates,Paleocortices,Periallocortices,Plate, Cortical
D003342 Corpus Striatum Striped GRAY MATTER and WHITE MATTER consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the THALAMUS in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The WHITE MATTER is the INTERNAL CAPSULE. Lenticular Nucleus,Lentiform Nucleus,Lentiform Nuclei,Nucleus Lentiformis,Lentiformis, Nucleus,Nuclei, Lentiform,Nucleus, Lenticular,Nucleus, Lentiform,Striatum, Corpus
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
February 1987, Acta neurologica Scandinavica,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
November 1994, Brain research,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
March 1987, Acta neurologica Scandinavica,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
June 2014, Molecular imaging and biology,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
January 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
April 1986, Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
January 2019, Methods in molecular biology (Clifton, N.J.),
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
July 2004, Psychopharmacology,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
January 1987, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology,
K Leenders, and P Hartvig, and L Forsgren, and G Holmgren, and B Almay, and S A Eckernäs, and H Lundqvist, and B Långström
April 1998, Neurology,
Copied contents to your clipboard!