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We report construction of a genetic linkage map for the mosquito, Aedes aegypti, based on restriction fragment length polymorphisms (RFLPs). The map consists of 50 DNA markers that identify 53 loci covering 134 map units across three linkage groups. Determination of linkage associations between RFLP markers and several mutant marker loci allowed for partial integration of the RFLP markers with an existing classical genetic linkage map for A. aegypti. The RFLP markers include 42 random cDNA clones, three random genomic DNA clones, and five cDNA clones of known genes. We discuss the influence of autosomal sex determination, characteristic of culicine mosquitoes, in relation to its observed influence on segregation ratios. This has important ramifications for future efforts to identify quantitative trait loci associated with the ability of these mosquitoes to transmit various pathogens and parasites to man and other animals.
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
May 1980,
American journal of human genetics,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
September 1988,
Proceedings of the National Academy of Sciences of the United States of America,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
October 1986,
Proceedings of the National Academy of Sciences of the United States of America,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
July 1989,
The Plant cell,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
April 2001,
Genome,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
October 1988,
Nature,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
December 1992,
Genetics,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
June 1992,
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
January 1987,
Methods in enzymology,
D W Severson, and
A Mori, and
Y Zhang, and
B M Christensen
February 1992,
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik,
