-transparent.png){kind=logo}
To evaluate the pharmacological effects of ibudilast on cerebral circulation, we examined 5 ischaemic stroke patients, using positron emission tomography, and we measured cerebral blood flow (CBF). Ibudilast loading per os led to a remarkable increase in CBF after 30 min. This CBF elevation was observed in the lesion side as well as in the nonlesion hemisphere. Therefore, we can confirm that ibudilast ameliorates the chronic low perfusion state of CBF in the ischaemic stroke patient.
Related Publications
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
March 1974,
Acta neurologica,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
May 1986,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
September 1990,
No shinkei geka. Neurological surgery,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
January 1991,
Annual review of pharmacology and toxicology,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
January 1989,
Acta neurochirurgica,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
February 1976,
No to shinkei = Brain and nerve,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
January 1952,
Helvetica physiologica et pharmacologica acta,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
November 1957,
Munchener medizinische Wochenschrift (1950),
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
January 2002,
Klinicheskaia meditsina,
H Fukuyama, and
J Kimura, and
S Yamaguchi, and
H Yamauchi, and
M Ogawa, and
T Doi, and
Y Yonekura, and
J Konishi
October 1963,
Zeitschrift fur Kreislaufforschung,
