-transparent.png){kind=logo}
Proliferating cell nuclear antigen (PCNA) expression was studied in 103 gallbladder carcinomas and 23 metastatic lesions as well as in 25 control non-neoplastic gallbladder specimens. Positive nuclear staining was observed in 88% of controls, in 92% of carcinomas and in 70% of metastases. The mean number of positive cells was 21.2% in controls, 44.1% in primary carcinomas and 32% in metastatic cancer cells. Differences which were significant were control v. primary tumour, P < 0.000001; control v. metastasis, P < 0.01 and primary tumour v. metastasis, P < 0.006. In 57 (60%) of the primary tumours there was positive staining in over 40% of tumour cells. We were not able to demonstrate any relationship between macroscopic or microscopic features and PCNA expression. However, tumours confined to the mucosa expressed PCNA more frequently than did more advanced tumours.
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
February 1995,
Zhonghua wai ke za zhi [Chinese journal of surgery],
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
July 1995,
Zhonghua wai ke za zhi [Chinese journal of surgery],
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
May 1997,
Journal of surgical oncology,
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
February 1995,
British journal of urology,
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
January 1993,
Journal of cancer research and clinical oncology,
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
August 1996,
Journal of clinical pathology,
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
July 1995,
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics,
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
October 1993,
Journal of cutaneous pathology,
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
June 2015,
Journal of clinical and diagnostic research : JCDR,
I Roa, and
J Araya, and
T Shiraishi, and
R Yatani, and
M Villaseca, and
I Wistuba, and
X De-Aretxabala
September 1995,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
