Native American families have powerful reservoirs for resilience. Many families experience oppression, exploitation, and poverty that contribute to mental health disturbances. Cultural traditions associated with harmony can promote positive mental health for Native American children and adolescents. Health care providers will benefit from knowing risks, cultural expressions of coping, and a framework for contextual assessment and intervention. The purpose of this paper is to respond to the challenge of developing practices, programs, and policies that are culturally sensitive and helpful for people who need nursing care.