-transparent.png){kind=logo}
The mechanism of stimulation of DNA synthesis by microtubule-associated protein 2 (MAP2) was examined in the nuclear matrix isolated from Physarum polycephalum. Porcine brain MAP2 stimulated DNA synthesis by the matrix with exogenous templates, but not with endogenous templates. Kinetic analyses showed that MAP2 decreases the Km of the matrix for deoxyribonucleoside triphosphates. Comparison of the Km values of active- and latent-type DNA replication machineries of Physarum suggested a possible role for MAPs or MAP-like proteins in DNA replication.
Related Publications
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
April 1989,
Biochimica et biophysica acta,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
December 1979,
Biochemical and biophysical research communications,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
March 1989,
Biochemical and biophysical research communications,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
January 1967,
Biochimica et biophysica acta,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
November 1965,
Biochemical and biophysical research communications,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
January 1986,
Molecular biology reports,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
June 1982,
Journal of cell science,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
June 1987,
Cell structure and function,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
May 1974,
European journal of biochemistry,
M Shioda, and
K Okuhara, and
K Murakami-Murofushi, and
H Murofushi
January 1981,
Nucleic acids research,
