Biomaterial Database

Calcium level affects the efficacy of supplemental microbial phytase in corn-soybean meal diets of weanling pigs. 1994

X G Lei, and P K Ku, and E R Miller, and M T Yokoyama, and D E Ullrey

Animal Science Department, Michigan State University, East Lansing 48824.

A 2 x 2 x 2 factorial experiment was conducted with 64 pigs (4 wk old, 8.04 +/- .50 kg BW) to determine the effect of various dietary concentrations of Ca, vitamin D, and microbial phytase (Aspergillus niger) on phytate-P utilization. A low-P, corn-soybean meal diet was supplemented with two levels of phytase (unit/gram), 750 (suboptimal) and 1,200 (optimal); of vitamin D (international unit/kilogram), 660 (normal) and 6,660 (high); and of Ca (percentage), .4 (low) and .8 (normal). Pen feed consumption and individual pig weights, plasma inorganic P and Ca concentrations, and plasma alkaline phosphatase (AP) activity were measured at d 10, 20, and 30. The normal dietary Ca concentration had an adverse effect (P < .05) on all the response measures. The depressive effect of the normal dietary Ca on performance was greater (P < .05) at the normal vitamin D level or at the optimal phytase level than at the other levels of these two factors. The elevation in plasma AP activity in pigs fed the normal dietary Ca was greater (P < .05) at the suboptimal than at the optimal phytase level. The decreases in plasma inorganic P concentration and increases in plasma Ca concentration associated with the normal dietary Ca were substantial. In conclusion, the normal level of Ca in the diet greatly reduced the efficacy of supplemental phytase. Raising vitamin D in the diet partially offset this adverse effect but did not produce further improvement when the Ca level was low.

UI	MeSH Term	Description	Entries
D010758	Phosphorus	A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.	Black Phosphorus,Phosphorus-31,Red Phosphorus,White Phosphorus,Yellow Phosphorus,Phosphorus 31,Phosphorus, Black,Phosphorus, Red,Phosphorus, White,Phosphorus, Yellow
D010832	6-Phytase	An enzyme that catalyzes the conversion of myo-inositol hexakisphosphate and water to 1L-myo-inositol 1,2,3,4,5-pentakisphosphate and orthophosphate. EC 3.1.3.26.	Phytase,6 Phytase
D010833	Phytic Acid	Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.	Inositol Hexaphosphate,Phytin,Calcium Phytate,Inositol Hexakisphosphate,Phytate,Sodium Phytate,Acid, Phytic,Hexakisphosphate, Inositol,Hexaphosphate, Inositol,Phytate, Calcium,Phytate, Sodium
D011897	Random Allocation	A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.	Randomization,Allocation, Random
D002118	Calcium	A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.	Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D002136	Calcium, Dietary	Calcium compounds in DIETARY SUPPLEMENTS or in food that supply the body with calcium.	Dietary Calcium
D003313	Zea mays	A plant species of the family POACEAE. It is a tall grass grown for its EDIBLE GRAIN, corn, used as food and animal FODDER.	Corn,Indian Corn,Maize,Teosinte,Zea,Corn, Indian
D004435	Eating	The consumption of edible substances.	Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D005527	Food, Fortified	Any food that has been supplemented with essential NUTRIENTS either in quantities that are greater than those normally present, or which are not found in the food typically. Fortified food also includes food enriched by adding various nutrients to compensate for those removed by refinement or processing. (Modified from Segen, Dictionary of Modern Medicine, 1992).	Enriched Food,Food, Supplemented,Enriched Foods,Food, Enriched,Foods, Enriched,Foods, Fortified,Foods, Supplemented,Fortified Food,Fortified Foods,Supplemented Food,Supplemented Foods
D000469	Alkaline Phosphatase	An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.