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Choroidal malign melanoma showing rapid progression in a boy 17 years old is presented. The patient was under therapy with methoxy psoralen + Ultraviolet A (PUVA)* for psoriasis vulgaris. He had undergone complete ophthalmologic examinations with three-month intervals from the beginning of this therapy. The tumor was detected in the seventh month, rapidly enlarging within the next twenty days, and eventually leading to enucleation. PUVA is known to be a risk factor for cutaneous malign melanoma. However, there is no reported incidence of choroidal malign melanoma in PUVA treated patients. To our knowledge, this is the only case showing the possible role of PUVA therapy as a predisposing factor in the development of uveal malign melanoma.
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
January 1981,
Developments in ophthalmology,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
January 1993,
Optometry clinics : the official publication of the Prentice Society,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
February 1986,
Bulletin des societes d'ophtalmologie de France,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
January 1984,
Progress in clinical and biological research,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
November 1983,
American journal of ophthalmology,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
April 1982,
Journal of clinical ultrasound : JCU,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
June 1998,
The British journal of dermatology,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
June 1987,
Annals of ophthalmology,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
January 1986,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
G Haciyakupoğlu, and
I Varinli, and
H R Memişoğlu, and
S Varinli, and
N Demircan, and
G Denli
November 1985,
British journal of hospital medicine,
