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New peptide boronic acid inhibitors of thrombin.
1993
S Elgendy, and J Deadman, and G Claeson
Thrombosis Research Institute, London.
Associated MeSH Terms
Cite
UI
MeSH Term
Description
Entries
D009842
Oligopeptides
Peptides composed of between two and twelve amino acids.
Oligopeptide
D001896
Boron Compounds
Inorganic or organic compounds that contain boron as an integral part of the molecule.
Borides,Compounds, Boron
D001665
Binding Sites
The parts of a macromolecule that directly participate in its specific combination with another molecule.
Combining Site,Binding Site,Combining Sites,Site, Binding,Site, Combining,Sites, Binding,Sites, Combining
D013917
Thrombin
An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.
Thrombase,Thrombin JMI,Thrombin-JMI,Thrombinar,Thrombostat,alpha-Thrombin,beta,gamma-Thrombin,beta-Thrombin,gamma-Thrombin,JMI, Thrombin
D015394
Molecular Structure
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Structure, Molecular,Molecular Structures,Structures, Molecular
Related Publications
S Elgendy, and J Deadman, and G Claeson
Peptide boronic acid inhibitors of thrombin.
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Anticoagulant activity of a peptide boronic acid thrombin inhibitor by various routes of administration in rats.
January 1991, Peptides,
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Selection of S18326 as a new potent and selective boronic acid direct thrombin inhibitor.
October 1997, Thrombosis and haemostasis,
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Boronic acid inhibitors of porcine pancreatic lipase.
June 1980, The Journal of biological chemistry,
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Design, synthesis and biological evaluation of novel non-peptide boronic acid derivatives as proteasome inhibitors.
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A new peptide boronic acid inhibitor of elastase-induced lung injury in hamsters.
April 1986, The American review of respiratory disease,
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