Biomaterial Database

Parathyroid hormone-related protein: physiology and pathophysiology. 1994

F Law, and S Ferrari, and R Rizzoli, and J P Bonjour

Department of Medicine, University Hospital, Geneva, Switzerland.

UI	MeSH Term	Description	Entries
D010281	Parathyroid Hormone	A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.	Natpara,PTH (1-84),PTH(1-34),Parathormone,Parathyrin,Parathyroid Hormone (1-34),Parathyroid Hormone (1-84),Parathyroid Hormone Peptide (1-34),Hormone, Parathyroid
D011506	Proteins	Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.	Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D044162	Parathyroid Hormone-Related Protein	A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.	Hypercalcemic Hormone of Malignancy,PTH Like Tumor Factor,PTH-Like Protein,PTH-Related Peptide,PTHrP,Parathyroid Hormone Like Tumor Factor,Parathyroid Hormone-Like Protein,Parathyroid Hormone-Related Peptide,Tumor Hypercalcemic Factor,Hormone-Related Protein, Parathyroid,Hypercalcemic Factor, Tumor,PTH Like Protein,PTH Related Peptide,Parathyroid Hormone Like Protein,Parathyroid Hormone Related Peptide,Parathyroid Hormone Related Protein