Biomaterial Database

An epidemiological study of congenital malformations in newborn. 1993

P Chaturvedi, and K S Banerjee

Department of Pediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha.

In a prospective study of 3000 consecutive deliveries (14 twin deliveries), the rate of congenital malformation was reported to be 27.20 per 1000 births (82 out of 3014). No significant difference was observed in the frequency of congenital malformation in urban rural status, in different religion and caste, and in male female babies. An increase in frequency was seen in advanced maternal age and in primi and fourth gravida mothers. A number of environmental factors studied, such as use of different tooth powders, type of drinking water, different cooking vessels, associated vitamin deficiencies did not seem to influence the prevalence of birth defects significantly. The factors which significantly increased the rate of congenital malformation were consanguinity in parents, heredofamilial history of malformations, presence of hydramnios, maternal febrile illness in first trimester, past history of abortion and history of progesterone intake during pregnancy.

UI	MeSH Term	Description	Entries
D007194	India	A country in southern Asia, bordering the Arabian Sea and the Bay of Bengal, between Burma and Pakistan. The capitol is New Delhi.	Republic of India
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297	Male		Males
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000013	Congenital Abnormalities	Malformations of organs or body parts during development in utero.	Birth Defects,Congenital Defects,Deformities,Fetal Anomalies,Fetal Malformations,Abnormalities, Congenital,Defects, Congenital,Abnormality, Congenital,Anomaly, Fetal,Birth Defect,Congenital Abnormality,Congenital Defect,Defect, Birth,Defect, Congenital,Deformity,Fetal Anomaly,Fetal Malformation,Malformation, Fetal
D000014	Abnormalities, Drug-Induced	Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.	Drug-Induced Abnormalities,Abnormalities, Drug Induced,Abnormality, Drug-Induced,Drug Induced Abnormalities,Drug-Induced Abnormality
D012959	Socioeconomic Factors	Social and economic factors that characterize the individual or group within the social structure.	Economic and Social Factors,Social Inequalities,Social Inequality,Social and Economic Factors,Socioeconomic Characteristics,Factors, Socioeconomic,High-Income Population,Land Tenure,Standard of Living,Characteristic, Socioeconomic,Factor, Socioeconomic,High Income Population,High-Income Populations,Inequality, Social,Living Standard,Living Standards,Population, High-Income,Socioeconomic Characteristic,Socioeconomic Factor,Tenure, Land