-transparent.png){kind=logo}
A glucose sensor intended for future use in diabetic patients undergoing major surgery is described. It involves glucose oxidase immobilised at a platinised activated carbon electrode (PACE). The sensor gave a nonoxygen dependent amperometric response in whole undiluted blood and did not require the use of electron mediators. In vitro studies in protein containing buffer using a flow cell indicated current densities of approximately 160 nA mm-2 mM-1 and a linear response over the range 0-20 mM. The operational stability of the sensor was at least 49 h in continuous use. In addition the sensor had a 90-99% response time of 1 min when used at a flow rate of 3 ml min-1 and showed a temperature dependence of 2.4% C-1. The results reported suggest significant advantages of this approach, for future use as a perioperative intra-vascular sensor for diabetic subjects, over previously reported glucose sensors.
K R Greenough, and
A W Skillen, and
C J McNeil
September 2015,
Masui. The Japanese journal of anesthesiology,
K R Greenough, and
A W Skillen, and
C J McNeil
May 2008,
Praxis,
K R Greenough, and
A W Skillen, and
C J McNeil
January 1980,
Acta medica Scandinavica,
K R Greenough, and
A W Skillen, and
C J McNeil
November 2012,
Masui. The Japanese journal of anesthesiology,
K R Greenough, and
A W Skillen, and
C J McNeil
June 2012,
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery,
K R Greenough, and
A W Skillen, and
C J McNeil
April 1994,
Zeitschrift fur arztliche Fortbildung,
K R Greenough, and
A W Skillen, and
C J McNeil
January 1991,
Diabetic medicine : a journal of the British Diabetic Association,
K R Greenough, and
A W Skillen, and
C J McNeil
January 2000,
American journal of medical quality : the official journal of the American College of Medical Quality,
K R Greenough, and
A W Skillen, and
C J McNeil
December 1993,
Diabetes care,
K R Greenough, and
A W Skillen, and
C J McNeil
February 2009,
Nederlands tijdschrift voor geneeskunde,
