Apparent pharmacokinetics of PCB components in growing pigs and lambs when fed a ration containing Aroclor 1254. 1976

R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske

Young growing lambs and pigs were fed a ration containing 200 ppm of Aroclor 1254 for 35 days and then switched to "clean" feed. Blood and fat samples were collected periodically throughout the experiment and analyzed for components of Aroclor 1254 and total PCB. Several components are apparently accumulated and eliminated at different rates within each species, as seen by comparing gas chromatograph tracings, accumulation ratios and apparent rate constants of elimination. Differences in accumulation and elimination of Aroclor components, some of which were apparently caused by differences in growth rates, were also seen between pigs and lambs. Variable growth rates of different species of food producing animals are an important factor to consider when dealing with tissue distribution and residues of polychlorinated biphenyls for determination of carcass disposition, as well as accumulation of toxic concentrations in the animal body.

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D011078 Polychlorinated Biphenyls Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants. PCBs,Polychlorinated Biphenyl,Polychlorobiphenyl Compounds,Biphenyl, Polychlorinated,Biphenyls, Polychlorinated,Compounds, Polychlorobiphenyl
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D003201 Computers Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations. Calculators, Programmable,Computer Hardware,Computers, Digital,Hardware, Computer,Calculator, Programmable,Computer,Computer, Digital,Digital Computer,Digital Computers,Programmable Calculator,Programmable Calculators
D000273 Adipose Tissue Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white. Fatty Tissue,Body Fat,Fat Pad,Fat Pads,Pad, Fat,Pads, Fat,Tissue, Adipose,Tissue, Fatty
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000821 Animal Feed Foodstuff used especially for domestic and laboratory animals, or livestock. Fodder,Animal Feeds,Feed, Animal,Feeds, Animal,Fodders
D012756 Sheep Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS. Ovis,Sheep, Dall,Dall Sheep,Ovis dalli
D013552 Swine Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA). Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog

Related Publications

R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
July 1986, American journal of veterinary research,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
August 1983, Bulletin of environmental contamination and toxicology,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
September 2003, Chemosphere,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
March 2000, Bulletin of environmental contamination and toxicology,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
December 1983, Bulletin of environmental contamination and toxicology,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
August 1974, Bulletin of environmental contamination and toxicology,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
March 2008, Environmental toxicology and pharmacology,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
September 1981, Archives of environmental contamination and toxicology,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
January 1992, Bulletin of environmental contamination and toxicology,
R E Borchard, and M E Welborn, and L G Hansen, and R P Link, and R H Teske
January 1973, Journal of chromatography,
Copied contents to your clipboard!