Cadmium, copper, lead and zinc concentrations in hair and toenails of young children and family members: a follow-up study. 1994

M Wilhelm, and I Lombeck, and F K Ohnesorge
Institute of Toxicology, Children's Hospital, Heinrich-Heine-University of Düsseldorf, Germany.

In a follow-up study concentrations of cadmium, copper, lead and zinc (measured by atomic absorption spectrometry) in scalp hair and toenail clippings of 47 children (5-9 years) were compared with previous values (2 years earlier). Family members were also monitored. Twenty-five of the children selected have had either high hair values of Cd, Cu, Pb or low hair Zn concentrations or combinations of these (group A) in the first study. Control group comprised 22 children (B). At the follow-up study, there were no more differences between group A and B. Between the first and follow-up study Cd and Pb levels in hair and toenails of group A children declined (geometric means; hair Cd: 265 vs. 111 ng/g; hair Pb: 10.1 vs. 3.8 micrograms/g; toenail Cd: 720 vs. 335 ng/g; toenail Pb 18.5 vs. 5.8 micrograms/g) and hair Zn values increased (54 vs. 103 micrograms/g). Fathers of exposed children had more Cd and Pb in hair and toenails than fathers of control children (hair Cd: 88 vs. 48 ng/g; hair Pb: 4.4 vs. 1.3 micrograms/g; toenail Cd: 46 vs. 23 ng/g; toenail Pb: 1.3 vs. 0.7 microgram/g). No conclusive findings were obtained for Cu. With respect to heavy metal levels of mothers and brothers and sisters there was no uniform pattern. Children < 5 years of age are especially prone to higher Cd, Pb exposure and to lower Zn status compare with older children.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007854 Lead A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.
D008297 Male Males
D009262 Nails The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates. Fingernails,Toenails,Fingernail,Nail,Toenail
D002104 Cadmium An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D003300 Copper A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. Copper-63,Copper 63
D005190 Family A social group consisting of parents or parent substitutes and children. Family Life Cycles,Family Members,Family Life Cycle,Family Research,Filiation,Kinship Networks,Relatives,Families,Family Member,Kinship Network,Life Cycle, Family,Life Cycles, Family,Network, Kinship,Networks, Kinship,Research, Family
D005260 Female Females

Related Publications

M Wilhelm, and I Lombeck, and F K Ohnesorge
March 1990, The Science of the total environment,
M Wilhelm, and I Lombeck, and F K Ohnesorge
February 1985, Bulletin of environmental contamination and toxicology,
M Wilhelm, and I Lombeck, and F K Ohnesorge
July 2005, Biological trace element research,
M Wilhelm, and I Lombeck, and F K Ohnesorge
November 1974, Bulletin of environmental contamination and toxicology,
M Wilhelm, and I Lombeck, and F K Ohnesorge
January 1996, Roczniki Panstwowego Zakladu Higieny,
M Wilhelm, and I Lombeck, and F K Ohnesorge
January 1992, Archives of andrology,
M Wilhelm, and I Lombeck, and F K Ohnesorge
April 1986, Bulletin of environmental contamination and toxicology,
M Wilhelm, and I Lombeck, and F K Ohnesorge
February 2002, Biological trace element research,
M Wilhelm, and I Lombeck, and F K Ohnesorge
January 1983, Developmental pharmacology and therapeutics,
M Wilhelm, and I Lombeck, and F K Ohnesorge
January 1997, Roczniki Panstwowego Zakladu Higieny,
Copied contents to your clipboard!