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The loss of mitochondrial DNA was found in a cytoplasmic respiration-deficient mutant of yeast, strain N-1, induced by treatment of a normal yeast with 4-nitroquinoline 1-oxide. In cesium chloride density gradient centrifugation, mitochondrial DNA from the normal yeast showed a density of 1.684 g/ml, but mitochondrial fraction of respiration-deficient mutant strain N-1 had no detectable DNA at a densty of 1.684 g/ml or near it. Though an incorporation of 3H-adenine into mitochondrial DNA was amplified by the presence of cyclohemimide, the mutant had no detectable radioactivity in its mitochondrial fractions. Accordingly, it was concluded that respiration-deficient mutant strain N-1 has lost its mitochondrial DNA which was indispensable for the respiratory activity of yeast cells.
T Morita, and
M Fukunaga, and
I Mifuchi
January 1969,
Mutation research,
T Morita, and
M Fukunaga, and
I Mifuchi
February 1974,
Gan,
T Morita, and
M Fukunaga, and
I Mifuchi
June 1963,
Gan,
T Morita, and
M Fukunaga, and
I Mifuchi
October 1969,
Acta medicinae Okayama,
T Morita, and
M Fukunaga, and
I Mifuchi
April 1972,
Igaku to seibutsugaku. Medicine and biology,
T Morita, and
M Fukunaga, and
I Mifuchi
February 1976,
Mutation research,
T Morita, and
M Fukunaga, and
I Mifuchi
December 1987,
Zhonghua wai ke za zhi [Chinese journal of surgery],
T Morita, and
M Fukunaga, and
I Mifuchi
March 1966,
Igaku to seibutsugaku. Medicine and biology,
T Morita, and
M Fukunaga, and
I Mifuchi
August 1963,
Japanese journal of microbiology,
T Morita, and
M Fukunaga, and
I Mifuchi
December 1991,
Japanese journal of cancer research : Gann,
