Therapeutic donor insemination: fresh versus frozen. 1994

E M Barlet, and L L Penney
Department of Obstetrics and Gynecology, University of Missouri-Columbia Health Sciences Center.

Therapeutic donor insemination is used in the treatment of male factor infertility with the use of cryopreserved semen being the standard of care. We reviewed the therapeutic donor insemination (TDI) program at the University of Missouri. Data from TDI cycles between January, 1985 and October 1988, using fresh semen, were retrospectively reviewed and compared to cycles using frozen semen between November, 1988 and April, 1991. Pregnancy rates were 60% and 49% for fresh and frozen cycles respectively with monthly fecundabilities of 0.10 and 0.086 respectively. These rates are comparable to those achieved in other centers. Additionally, as found in most other TDI programs, analysis reveals no statistically significant difference in fecundability with the use of a fresh specimen over frozen semen.

UI MeSH Term Description Entries
D007247 Infertility, Female Diminished or absent ability of a female to achieve conception. Sterility, Female,Sterility, Postpartum,Sub-Fertility, Female,Subfertility, Female,Female Infertility,Female Sterility,Female Sub-Fertility,Female Subfertility,Postpartum Sterility,Sub Fertility, Female
D007248 Infertility, Male The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility. Sterility, Male,Sub-Fertility, Male,Subfertility, Male,Male Infertility,Male Sterility,Male Sub-Fertility,Male Subfertility,Sub Fertility, Male
D007316 Insemination, Artificial, Heterologous Human artificial insemination in which the semen used is that of a man other than the woman's husband. Insemination, Artificial, Human Donor,AID,Artificial Insemination, Donor,Heterologous Insemination,Insemination, Heterologous,Donor Artificial Insemination,Insemination, Donor Artificial
D008297 Male Males
D008923 Missouri State bounded on the east by Illinois and Kentucky, on the south by Arkansas, on the west by Kansas, and on the north by Iowa.
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000022 Abortion, Spontaneous Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference. Abortion, Tubal,Early Pregnancy Loss,Miscarriage,Spontaneous Abortion,Abortions, Spontaneous,Abortions, Tubal,Early Pregnancy Losses,Loss, Early Pregnancy,Losses, Early Pregnancy,Miscarriages,Pregnancy Loss, Early,Pregnancy Losses, Early,Spontaneous Abortions,Tubal Abortion,Tubal Abortions
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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