Biomaterial Database

[The normal range for albumin and immunoglobulin g concentration in the cerebrospinal fluid of children determined by radial immunodiffusion (author's transl)]. 1976

N Liappis, and A Jäkel

By the aid of the radial immunodiffusion method immunoglobulin G and albumin concentration were determined in cerebrospinal fluid of 58 boys and 47 girls (ages 1 month - 14 years). On the basis of clinical criterions these children were considered to be "healthy". The total number of examined children was 1200. RESULTS The sex-specific investigation of the 1 month-2 years and the 2-14 years old children showed no statistical significant differences. But the agespecific investigation revealed that the immunoglobulin G concentration in the cerebrospinal fluid of the older girls was statistically significant higher as compared to the younger girls and that the albumin concentration in the cerebrospinal fluid of the older boys was statistically significant lower than in the younger boys. The immunoglobulin G/albumin quotient was statistically significant higher in the group of older girls as compared to the group of younger girls.

UI	MeSH Term	Description	Entries
D007074	Immunoglobulin G	The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.	Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008297	Male		Males
D008433	Mathematics	The deductive study of shape, quantity, and dependence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Mathematic
D002556	Cerebrospinal Fluid Proteins	Proteins in the cerebrospinal fluid, normally albumin and globulin present in the ratio of 8 to 1. Increases in protein levels are of diagnostic value in neurological diseases. (Brain and Bannister's Clinical Neurology, 7th ed, p221)	Proteins, Cerebrospinal Fluid,Fluid Proteins, Cerebrospinal
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D005260	Female		Females
D005779	Immunodiffusion	Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction.	Gel Diffusion Tests,Diffusion Test, Gel,Diffusion Tests, Gel,Gel Diffusion Test,Immunodiffusions,Test, Gel Diffusion,Tests, Gel Diffusion
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man