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Serum bioactive but not immunoreactive interleukin-6 (IL-6), and serum C-reactive protein (CRP), have been reported to be of prognostic significance in multiple myeloma (MM). We measured serum immunoreactive IL-6 by a sensitive enzyme-linked immunosorbent assay in 30 MM patients at diagnosis. In 30% of the patients serum immunoreactive IL-6 exceeded the upper reference limit. The concentrations of CRP and IL-6 showed a linear association. Logarithmically transformed IL-6, CRP and beta 2-microglobulin were significant variables by univariate survival analysis; by multivariate analysis CRP was a slightly stronger prognostic factor than IL-6 and the only one of independent prognostic significance.
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
July 1995,
Blood,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
February 1994,
British journal of haematology,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
August 1994,
British journal of haematology,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
January 2008,
Clinical chemistry and laboratory medicine,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
October 2001,
Gastrointestinal endoscopy,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
May 2004,
Journal of the European Academy of Dermatology and Venereology : JEADV,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
July 1992,
Transplantation,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
March 2020,
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
December 2022,
Journal of clinical medicine,
A Tienhaara, and
K Pulkki, and
K Mattila, and
K Irjala, and
T T Pelliniemi
October 1991,
British journal of haematology,
