-transparent.png){kind=logo}
Platelet serotonin uptake was measured in 10 duodenal ulcer patients and 10 controls by determining the concentration of radioactivity in platelets after incubation with tritium-labelled serotonin binoxalate. Platelet 5-HT uptake in ulcer patients (312.0 +/- 125.0 CPM/10(7) platelets) was significantly higher than that in the control group (186.0 +/- 53.0 CPM/10(7) platelets; p < 0.01). Since the kinetics of 5-HT uptake by platelets may be a reflector of enhanced serotonergic activity, this finding may have implications in future therapeutic strategies for this disease.
Related Publications
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
January 1982,
Biological psychiatry,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
January 1991,
International clinical psychopharmacology,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
May 1983,
Digestive diseases and sciences,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
June 1982,
Cephalalgia : an international journal of headache,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
October 1990,
Biological psychiatry,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
January 1986,
Journal of affective disorders,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
September 1990,
Scandinavian journal of gastroenterology,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
October 1989,
Psychiatry research,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
July 1991,
Acta psychiatrica Scandinavica,
R Misra, and
R Komandur, and
M Chandra, and
K Shankar, and
S M Zaheer, and
S Ram, and
V R Gujrati
September 1991,
Biological psychiatry,
