-transparent.png){kind=logo}
Rats given five consecutive daily electroconvulsive shock (ECS) treatments and trained to run in the Morris water maze, starting three days posttreatment, showed deficits in learning and memory functions. Treatment before each training session with the thyrotropin-releasing hormone (TRH) analog NS-3 [(CG-3703), (3R),(6R)-6-methyl-5-oxo-3-thiomorphorinyl-l-histidyl-l-prolinamid e tetrahydrate] reversed these behavioral deficits. The possible use of TRH and its analogs as therapeutic treatment for the cognitive dysfunctions resulting from electroconvulsive shock treatment for depression and the possible involvement of central cholinergic systems in the cognitive dysfunctions are discussed.
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
February 1996,
Pharmacology, biochemistry, and behavior,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
August 1995,
Pharmacology, biochemistry, and behavior,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
January 1989,
Peptides,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
January 1992,
Peptides,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
June 1996,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
May 1996,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
August 1996,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
September 1989,
Behavioral and neural biology,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
October 1998,
Progress in neuro-psychopharmacology & biological psychiatry,
A Khan, and
H Lai, and
Y Ukai, and
M H Mirolo
August 1996,
Journal of the autonomic nervous system,
