Perforated gastric ulcers: resection compared with simple closure. 1993

P M Hewitt, and J Krige, and P C Bornman
Dept. of Surgery, University of Cape Town, South Africa.

One hundred thirty-four patients with perforated gastric ulcers who underwent emergency surgery at a tertiary referral center during a 20-year period were reviewed. Short-term outcome of 94 patients whose perforation was simply closed was compared with 40 who had a gastrectomy. Morbidity (simple closure 51%; resection 45%) and mortality (simple closure 10.6%; resection 7.5%) were similar, but four deaths after simple closure were procedure-related. In patients older than 65 years, morbidity (67%) and mortality (24%) increased significantly. The higher mortality in the elderly was particularly apparent after simple closure (29% vs 11%), but this may reflect selection bias. Simple closure is safe and effective in the majority of patients with perforated gastric ulcers. However, our data indicate that gastrectomy can be performed safely even in high risk cases and should be considered where there is a well documented history of chronicity or when the nature of the ulcer, or associated ulcer hemorrhage, preclude safe simple closure.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009017 Morbidity The proportion of patients with a particular disease during a given year per given unit of population. Morbidities
D010439 Peptic Ulcer Perforation Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY. Peptic Ulcer Perforations,Perforation, Peptic Ulcer,Perforations, Peptic Ulcer,Ulcer Perforation, Peptic,Ulcer Perforations, Peptic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old

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