[The effect of solubilized methandrostenolone on muscle hypertrophy and on the blood biochemical indices in rats]. 1993

A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous

The paper outlines a new mode of intravascular anabolic steroidal transport. The single intravenous administration of metandrostenolone aqueous solution to rats increases hypertrophy rate of MM. plantaris. It was shown that the action of a single dose (0.05 mg/kg) exceeded that of metandrostenolone oil solution in a dose of 5 mg/kg. The multiple reduction of doses of the anabolic drug and the high level of bioavailability were achieved. This effect was explained by the application of the specific transport agent.

UI MeSH Term Description Entries
D006984 Hypertrophy General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA). Hypertrophies
D008297 Male Males
D008696 Methandrostenolone A synthetic steroid with anabolic properties that are more pronounced than its androgenic effects. It has little progestational activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1188) Dehydromethyltestosterone,Metandienone,Methandienone,Dianabol,Metanabol,Nerobol
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D001769 Blood The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012995 Solubility The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Solubilities
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D017208 Rats, Wistar A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain. Wistar Rat,Rat, Wistar,Wistar Rats

Related Publications

A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
July 2015, Environmental toxicology and pharmacology,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
February 2006, Georgian medical news,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
January 1980, Toxicology,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
January 1975, Farmakologiia i toksikologiia,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
May 1970, Endocrinologia e scienza della costituzione,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
January 1965, Problemy endokrinologii i gormonoterapii,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
January 2018, Klinicheskaia laboratornaia diagnostika,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
January 2003, Annals of nutrition & metabolism,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
January 1972, Farmakologiia i toksikologiia,
A V Samoĭlov, and R D Seĭfulla, and N O Kamaev, and T A Tunitskaia, and N P Teplova, and A Ia Karmanovskiĭ, and M V Belous
January 1991, Patologicheskaia fiziologiia i eksperimental'naia terapiia,
Copied contents to your clipboard!