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1. The effect of membrane phospholipid composition and fluidity on tyrosine kinase activity was investigated in rat liver plasma membranes. 2. The phospholipid composition has been modified by in vitro enrichment of plasma membranes with different phospholipids in the presence of lipid transfer proteins and by partial delipidation with exogenous phospholipases A2, C and D and subsequent enrichment with phosphatidylglycerol. 3. Phosphatidylglycerol and dioleoylglycerophosphocholine caused dramatic elevation of this activity, while phosphatidylserine and phosphatidylethanolamine were less effective. Enrichment with dipalmitoylglycerophosphocholine and sphingomyeline reduced tyrosine kinase activity.
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
January 1992,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
September 1997,
Cell biochemistry and function,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
January 1987,
Biochimie,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
January 1981,
Hepatology (Baltimore, Md.),
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
October 1992,
Biochemistry,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
March 2001,
Biochemical and biophysical research communications,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
November 1989,
Biochemical pharmacology,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
January 1982,
Cellular and molecular biology,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
May 1980,
Biochemistry,
N J Gavrilova, and
M S Setchenska, and
T T Markovska, and
A B Momchilova-Pankova, and
K S Koumanov
January 1995,
The Biochemical journal,
