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Biliary metabolites of rats receiving 3H labeled 2,5,2',5'-tetrachlorobiphenyl, a component of commercial polychlorinated bipheyl (PCB) mixtures include 3-OH-2,5,2',5'-tetrachlorobiphenyl and a dihydrodiol tentatively identified as trans-3,4-dihydrodihydroxy-2,5,2',5'-tetrachlorobiphenyl. Metabolism of PCBs in the rat probably occurs in part through an arene oxide intermediate.
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