Biomaterial Database

[Seasonal variations in 25-hydroxycholecalciferol in cord blood of newborn infants]. 1976

A Frédérich, and M Romand-Monnier, and B Loras, and M Dumont

An estimation of 25-hydroxycholecalciferol (25-OH-D3) by competitive proteic binding after silicic acid chromatography was performed in the cord blood of 130 neonates whose births were spaced throughout a whole year. The concentration of 25-OH-D3 is seen to rise regularly from May to August and then drops rapidly from September. The average value observed in the summer period (9,3 +/- 5,8 ng/ml) is worth twice the value of the cold season (4,7 +/- 1,7 ng/ml). A direct correlation can be seen ( y = 0,030 x + 1,68, r = 0,92, p less than 0,0001) between the average monthly rate (y: ng/ml) of 25-OH-D3 in the cord plasma and the number of sunny hours (x: hours/month) for the area concerned (Lyons, France) in the last month of pregnancy. This evidence suggests the possible existence of a relative vitamin D deficiency in the foetus and its possible cause as an aggravating feature in the hypocalcaemia of the neonate.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011263	Pregnancy Trimester, Third	The last third of a human PREGNANCY, from the beginning of the 29th through the 42nd completed week (197 to 294 days) of gestation.	Pregnancy, Third Trimester,Trimester, Third,Last Trimester,Last Trimesters,Pregnancies, Third Trimester,Pregnancy Trimesters, Third,Third Pregnancy Trimester,Third Pregnancy Trimesters,Third Trimester,Third Trimester Pregnancies,Third Trimester Pregnancy,Third Trimesters,Trimester, Last,Trimesters, Last,Trimesters, Third
D005260	Female		Females
D005312	Fetal Blood	Blood of the fetus. Exchange of nutrients and waste between the fetal and maternal blood occurs via the PLACENTA. The cord blood is blood contained in the umbilical vessels (UMBILICAL CORD) at the time of delivery.	Cord Blood,Umbilical Cord Blood,Blood, Cord,Blood, Fetal,Blood, Umbilical Cord,Bloods, Cord,Bloods, Fetal,Bloods, Umbilical Cord,Cord Blood, Umbilical,Cord Bloods,Cord Bloods, Umbilical,Fetal Bloods,Umbilical Cord Bloods
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006887	Hydroxycholecalciferols	Hydroxy analogs of vitamin D 3; (CHOLECALCIFEROL); including CALCIFEDIOL; CALCITRIOL; and 24,25-DIHYDROXYVITAMIN D 3.	Hydroxyvitamins D,Hydroxycholecalciferol
D012621	Seasons	Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Seasonal Variation,Season,Seasonal Variations,Variation, Seasonal,Variations, Seasonal
D013472	Sunlight	Irradiation directly from the sun.	Sunshine