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Type II pneumonocytes isolated from adult rats incorporate radioactivity from 1-[3H]hexadecanol into either lipids. The radioactivity is distributed between the neutral lipids, phosphatidylcholines, and phosphatidylethanolamines. The neutral lipid fraction is almost exclusively composed of triradylglycerols. The potent ether-containing glycerophospholipid, platelet-activating factor, has been shown to stimulate glycogen breakdown and surfactant secretion. In consideration that a long chain alcohol (hexadecanol) is added to certain artificial surfactant preparations which are utilized in the treatment of respiratory distress syndrome of the newborn, the metabolism of hexadecanol by the type II pneumonocytes should be taken into account.
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
February 1994,
Archives of biochemistry and biophysics,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
June 1989,
Biochimica et biophysica acta,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
June 1983,
The Biochemical journal,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
January 1979,
International review of cytology. Supplement,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
March 1987,
International journal of radiation biology and related studies in physics, chemistry, and medicine,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
January 1975,
Tissue & cell,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
January 1987,
Experimental lung research,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
January 1987,
Methods in enzymology,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
December 1985,
The Biochemical journal,
R A Frenkel, and
H Narahara, and
H Eguchi, and
K Toyoshima, and
J M Johnston
November 1979,
Infection and immunity,
