Phagocytosis of platelet in coronary heart disease patients with blood-stasis syndrome. 1993

J Wu, and K J Chen, and Y J Wu
Department of Clinical Pharmacology, Xiyuan Hospital, China Academy of Traditional Chinese Medicine, Beijing.

Phagocytosis of platelets was studied under electronmicroscope in 36 healthy persons and 64 coronary heart disease (CHD) patients with blood-stasis syndrome (BSS). The result showed that both the number of latex particles phagocytized by platelet and platelets which phagocytized latex particles were decreased in CHD with BSS. It was also found in this group that most of the platelets having active-phagocytosis were of medium size. The proportion of large platelets containing plentiful glycogen granules was much more in CHD patients with BSS and the shapes of platelets were changed readily with active exocytosis and aggregations. Therefore the present findings of disability of platelet phagocytosis might be considered the basic change in CHD with BSS.

UI MeSH Term Description Entries
D008297 Male Males
D008516 Medicine, Chinese Traditional A system of traditional medicine which is based on the beliefs and practices of the Chinese culture. Chinese Medicine, Traditional,Chung I Hsueh,Traditional Medicine, Chinese,Zhong Yi Xue,Chinese Traditional Medicine,Traditional Chinese Medicine,Traditional Tongue Assessment,Traditional Tongue Diagnosis,Hsueh, Chung I,Tongue Assessment, Traditional,Tongue Diagnoses, Traditional,Tongue Diagnosis, Traditional,Traditional Tongue Assessments,Traditional Tongue Diagnoses
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010587 Phagocytosis The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES). Phagocytoses
D001792 Blood Platelets Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation. Platelets,Thrombocytes,Blood Platelet,Platelet,Platelet, Blood,Platelets, Blood,Thrombocyte
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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