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Membrane fractions enriched in transverse tubules, either predominantly free or junctional, sarcoplasmic reticulum subfractions and purified sarcolemmal preparations have been isolated from rabbit skeletal muscle and examined for their contents of protein kinase C. Using activity measurements and immunoblotting methods, we have been able to detect substantial amounts of endogenous protein kinase C in T-tubules membranes and to a lesser extent, in muscle sarcolemma. Protein kinase C was found to be highest in junctional T-tubules and to be virtually absent from sarcoplasmic reticulum-derived membrane fractions. Immunofluorescence staining of muscle fibers is consistent with a T-tubule localization of the kinase. The T-tubule-associated protein kinase C enzyme phosphorylates several potentially important membrane proteins.
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
April 1992,
Muscle & nerve,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
January 2005,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
December 2004,
The Journal of physiology,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
January 1984,
Biochemical and biophysical research communications,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
January 2004,
American journal of veterinary research,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
February 2001,
Experimental cell research,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
November 1997,
The Biochemical journal,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
March 2000,
American journal of physiology. Endocrinology and metabolism,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
June 1984,
Journal of muscle research and cell motility,
S Salvatori, and
S Furlan, and
B Millikin, and
R Sabbadini, and
R Betto, and
A Margreth, and
G Salviati
December 1973,
Doklady Akademii nauk SSSR,
