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Dopamine (DA) is one of the putative neurotransmitters of the lateral efferent olivocochlear fibers. The cochlear DA content after noise exposure was analyzed using high-performance liquid chromatography coupled with electrochemical detection. Animals were exposed for 1 h to white noise at 70, 90 or 110 dB SPL or were kept in conditions of silence. Half of the animals were pretreated with piribedil, a D2 agonist, and the other half served as controls. In control (untreated) animals, noise stimulation resulted in a progressive decrease of cochlear DA concentration. This decrease was scarcely detected when animals were pretreated with piribedil. Present findings indicate that piribedil modifies cochlear DA turnover under noise stimulation.
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
January 1993,
Audiology : official organ of the International Society of Audiology,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
January 1978,
Neuropsychobiology,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
September 1980,
Life sciences,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
September 1974,
European journal of pharmacology,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
December 1974,
Clinical pharmacology and therapeutics,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
January 1988,
Physiology & behavior,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
October 1979,
Clinical endocrinology,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
July 2017,
Current neurology and neuroscience reports,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
January 1986,
Clinical neuropharmacology,
M A Vicente-Torres, and
P Gil-Loyzaga, and
P Fernández, and
A Arce, and
A Esquifino
January 1974,
Naunyn-Schmiedeberg's archives of pharmacology,
