Biomaterial Database

Abdominal neuroendocrine neoplasm with misplaced exocytosis. 1993

J A Tucker

Department of Pathology, University of South Alabama, Mobile 36617.

A 22-year-old man presented with epigastric fullness and tenderness. A 14-cm mass that was adherent to the sigmoid colon was removed surgically. The tumor exhibited ultrastructural evidence of neuroendocrine differentiation but defied precise classification. The tumor exhibited misplaced exocytosis, a finding not previously described in neuroendocrine tumors other than prolactin cell adenomas.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008854	Microscopy, Electron	Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.	Electron Microscopy
D005089	Exocytosis	Cellular release of material within membrane-limited vesicles by fusion of the vesicles with the CELL MEMBRANE.
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000008	Abdominal Neoplasms	New abnormal growth of tissue in the ABDOMEN.	Abdominal Neoplasm,Neoplasm, Abdominal,Neoplasms, Abdominal
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D018278	Carcinoma, Neuroendocrine	A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)	Carcinomas, Neuroendocrine,Neuroendocrine Carcinoma,Neuroendocrine Carcinomas